the withdrawal that reaches the soul's core
a certain percentage of people who’ve gotten so dependent on chemicals for feelings of well-being that when the chemicals have to be abandoned they undergo a loss-trauma that reaches way down deep into the soul’s core systems
Context
The Ennet-resident frame on the theme's border with depression: Kate Gompert's worst depression is not free-floating but a withdrawal — the loss-trauma of abandoning the chemical reaching "way down deep into the soul's core systems," the predator-grade It that arrives specifically as she Withdraws from secret marijuana. The substance-abandonment as the trigger the clinical picture is built on.