the drug that seals him off from everyone — "He couldn't even be around anyone…"
He couldn't even be around anyone else if he'd smoked marijuana that same day, it made him so self-conscious.
Context
Marijuana-thinking rendered as involution: thoughts jutting in jagged directions, the mind turned so far in on its own sagging self-consciousness that he has forbidden himself the company of any other person while high. The substance does not open him to anything, it walls him off, converting a life into a sequence of vectors between bedroom, refrigerator, and toilet with the blinds down and the phone message set to unreachable. The high is a hermetic seal.